Research
Traditional use and research
Lion's mane has a long history in traditional Chinese medicine, where it was used to support memory and digestion. In Japan it is called yamabushitake, after the pom-pom ornaments worn by mountain monks, and in China it is known as "monkey head mushroom."
Scientists are interested in two groups of compounds: hericenones, found in the fruiting body, and erinacines, found in the mycelium. In lab and animal studies, these compounds affect nerve growth factor, a protein that helps nerve cells grow and survive.
Human research is still early. A small number of clinical studies on memory and mood have produced mixed results, and there is not yet enough evidence to say lion's mane treats or prevents any condition. Supplements also vary widely in quality and labeling.
Talk to a doctor before taking lion's mane supplements, especially if you are pregnant, have mushroom allergies, or take medication. As a cooked food, it is generally considered safe.